Three-Chloromethcathinone (three-CMC), often known as clophedrone, is usually a synthetic material belonging for the cathinone class of psychoactive compounds. It is rather related in framework to other methcathinone derivatives for example 3-MMC and four-CMC.[1][2] Unlike cathinone, which happens naturally during the khat plant Catha edulis, three-CMC isn't found in nature https://designerlab.nl/research-chemicals/cathinonen/3cmc/