There's a release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors while in the dorsal horn to reduce afferent suffering transmission and make analgesia. For that reason, drugs like clonidine that focus on alpha-two receptors can affect the transmission of suffering. Clonidine treats higher blood https://bookmarkcitizen.com/story19820091/onolidine-an-overview